Advanced Instrumentation, Data Interpretation, and Control of Biotechnological Processes

Editor:
Jan F. M. Van Imple; Dirk M. Iserentant
Format:
Hardcover

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United States of America

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Advanced Instrumentation, Data Interpretation, and Control of Biotechnological Processes

Short description

The introduction of modern optimization and control strategies is lagging behind other engineering disciplines in the field of biotechnological processes. This book identifies two main reasons, and introduces a number of advanced techniques for dealing with them.

Long description

The scope of the field of biotechnological processes is very wide, covering such processes as fermentations for production of high-valued specialist chemicals (such as pharmaceuticals), high-volume production of foods and feeds (such as yoghurt, cheese and beer), as well as biological waste treatment, handling solid (composting), liquid (activated sludge) and gaseous wastes (biofilters). Compared to other engineering disciplines, the introduction of modern optimization and control strategies is lagging behind. Two main reasons can be identified. First, the living organisms (or part thereof) that are central to these processes make the mathematical modelling of the processes a difficult task and, since models are central to the development of control systems, the on-line control problem is also complex. The other difficulty stems from the absence, in most cases, of cheap and reliable instrumentation suited to real-time monitoring. In this book a number of advanced techniques for dealing with these problems are introduced.;The book is directed at engineers, researchers and students in the field of process control and systems theory as applied to industrial biotechnological processes, as well as at bioengineers who have some background in control engineering and wish to increase their understanding of how advanced control-theory applies to biological processes.

Product details

Publisher:
Springer
ISBN:
9780792348603
Publication date:
December 1997
Length:
156mm
Width:
234mm
Thickness:
27mm
Weight:
853g
Pages:
484
Illustrations:
Illustrated
Readership:
Professional & scholarly

Table of contents

  • Part 1 Hardware sensors: flow-injection analysis for on-line monitoring of a waste-water treatment plant
  • on-line measurement of viable biomass
  • membrane-inlet mass spectrometry for the characterization and monitoring of biotechnological processes
  • flow cytometry
  • microcalorimetric characterization of bacterial inocula. Part 2 Model-based control: on-line data acquisition
  • data processing for system identification
  • error diagnosis and data reconciliation using linear conservation relations
  • general concepts of bioprocess modelling
  • bioprocess model identification
  • optimal control of fed-batch fermentation processes
  • monitoring and adaptive control of bioprocesses
  • optimal-adaptive control of fed-batch fermentation processes
  • predictive control in biotechnology using fuzzy and neural models.

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Advanced Instrumentation, Data Interpretation, and Control of Biotechnological Processes

Advanced Instrumentation, Data Interpretation, and Control of Biotechnological Processes

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