Pincus is a New York City dentist with horrendous people skills. When a routine surgery goes awry, Pincus is pronounced dead, but is miraculously revived seven minutes later. The ill-mannered Manhattanite suffers only one lasting after-effect; the ability to see and speak with the dead. Word soon gets out in the spirit community and Pincus is irritated to discover he's the go-to-guy for every phantom with unfinished business in the city.
At the forefront of the ghostly mob is recently deceased Frank Herlihy (Greg Kinnear - Little Miss Sunshine, Baby Mama), who is determined to stop the remarriage of his widow, Gwen (Téa Leoni - Spanglish, Fun with Dick and Jane). The laughs unfold when the prickly and romantically inexperienced Pincus, smitten with Gwen, tries to woo her away from her betrothed - with hysterically awkward results.